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Right when it seemed as if Derrick Henry was legitimately pushing DeMarco Murray for a significant share of backfield work, the 2016 and early-2017 game plan was quickly put back in place. Murray racked up 18 touches for 69 yards on 49 snaps against Miami in Week 5. Henry touched the ball four times on 10 snaps. Murray has battled some injuries this season, but he still has played 97 more snaps than Henry. Murray is very much in the RB1 mix against the Colts’ struggling defense this week. Henry is a great handcuff but shouldn’t be in starting lineups.
Quarterback Marcus Mariota hasn’t played 16 games in an NFL season yet, and he won’t this year after missing Week 5 with a hamstring injury. The Titans are going nowhere without Mariota, so it becomes essential to keep him upright or they’ll be at home come playoff time once again. Backup Matt Cassel won’t get it done. There is optimism that Mariota will return in Week 6, but can he stay healthy? That’s the Titans’ biggest remaining question mark, and the fact there’s uncertainty reflects the overall vibe toward this team. — Cameron Wolfe
12.3 percent chance. If the Raiders played in any other division, their outlook might be better than it is in the AFC West. But with Derek Carr injured and with the Chiefs and Broncos a combined 8-1, Oakland’s chances have dipped to 12.3 percent after starting the season over 50 percent.
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36.8 percent chance. The Bills weren’t given much of a shot by FPI at the start of the season (11.6 percent), but their chances have tripled since then, thanks to a three-win start. The Bills get some rest this week, before they play three at home in a four-game stretch afterward.
Bradford played Monday night for the first time since Week 1. But the Vikings (3-2) removed him late in the second quarter, and Keenum led the team to a 20-17 victory over the Chicago Bears.
Bradford looked uncomfortable from the opening play and was limping noticeably by the time he gave way to Keenum. Sugarman said Bradford obviously aggravated the knee at some point during the game and pushed back strongly on suggestions that Bradford was not healthy enough to play in the first place.